… 39 (GPR39) as a microvascular smooth muscle cell (mVSMC) … us to isolate its binding proteins
from mouse heart mVSMCs … -activated (BKCa) and ATP-sensitive potassium channels, the …

… , or shear stress, endothelium-derived EETs act on smooth muscle cells to activate large
conductance, calcium-… in coronary smooth muscle through guanine nucleotide binding protein. …

… activation of KATP channels was also examined by using … Tunica media is mostly composed
of smooth muscle cells (SMCs) … AA can be converted into epoxyeicosatrienoic acids (EETs) …

… with reduced activation of the α subunits of G12 family G proteins (Gα 12/13 )/… guanosine
monophosphate (cGMP) level in cardiac tissue. In in vitro studies, cardiac fibroblast activation, …

… to the smooth muscle where they activate the large … EET release of tPA requires a guanine
nucleotide-binding protein, … MAP kinase prosurvival signaling mechanisms to prevent cardiac …

… Potassium channels importantly contribute to the regulation of vascular smooth muscle (VSM) …
conductance, Ca 2+ -activated K + (BK Ca ) channels, intermediate-conductance Ca 2+ -…

… the tonus of underlying vascular smooth muscle cells (VSMC) by … RhoA is activated by the
guanine nucleotide exchange … The small GTP-binding protein Rho binds to and activates a …

… guanine nucleotide binding protein … The fact that arachidonic acid was able to induce
vascular smooth muscle … of arachidonic acid ie 11,12- and 14,15-epoxyeicosatrienoic acid (EET) …

… adjacent smooth muscle … protein subunits (β and γ) activate a guanine nucleotide exchange
factor (Rho-GEF) to convert the small GTP-binding protein Rho from its inactive GDP-bound …

… Ca 2+ is increased by ion channels and transporters on the … This article focuses on endothelial
and smooth muscle Ca 2+ … of abnormal endothelial and smooth muscle Ca 2+ signals to …